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General » diabetes mellitus

  • Insulin Resistance & Prediabetes by Dr. Mariela Glandt Insulin Resistance & Prediabetes by Dr. Mariela Glandt

    Posted on by Anabelle Savion

    Insulin resistance and prediabetes occur when the body becomes insensitive to insulin.

    What is insulin?

    Insulin is a hormone made by the pancreas that helps glucose in your blood enter cells in your muscle, fat, and liver, where it’s used for energy. Glucose comes from the food you eat or it’s made by the liver when we are fasting. When glucose levels rise after you eat, your pancreas releases insulin into the blood, allowing the sugar to enter the cells and allowing the blood glucose levels to go back down to normal.

     

    What is insulin resistance?

    Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin and can’t easily take up glucose from your blood. Insulin resistance causes are highly correlated with abdominal fat (visceral fat). There are people that can handle a great deal of fat and don’t get sick, while there are others have less fat cells and therefore can contain limited amounts of fat. When the fat cells are overstuffed with fat, the fat starts sending a clear message that it does not have room for any more sugar.  This is called insulin resistance, and what it is essentially suggesting is that the body does not want any more sugar to come in. However, the pancreas must clear the high sugar from the blood and hence it makes more insulin to help glucose enter your cells. As long as your pancreas can make enough insulin to overcome your cells’ weak response to insulin, your blood glucose levels will stay in the healthy range. 

     

    Are there any problems with having insulin resistance, as long as glucose levels are in the normal range?

    Having normal sugar levels can be deceiving, giving a sense that there is no problem. However, high insulin levels, even with normal sugars, can be a problem. In the short run, high insulin levels make us hungry and make us gain weight. High insulin levels are also associated with hypertension and with dyslipidemia. In the long run, we know that high insulin levels are associated with higher rates of coronary artery disease, stroke, and cancer.

    What is prediabetes?

    When the pancreas is not able to keep up with the extra demand placed on it, then prediabetes sets in. This means your blood glucose levels are higher than normal but not high enough to be diagnosed as diabetes. One in every 3 adults has pre-diabetes. People with prediabetes have up to a 50 percent chance of developing diabetes over the next 5 to 10 years. Fortunately, type 2 diabetes can be prevented.

    What are the symptoms of insulin resistance and prediabetes?

    Insulin resistance and prediabetes usually have no symptoms. Unfortunately, doctors do not routinely check for insulin levels and diagnosed insulin resistance through other proxies. The presence of hypertension, high triglycerides, low HDL cholesterol, high uric acid, and fatty liver are all signs of insulin resistance. A HbA1c above 5.7 already points to insulin resistance. A HbA1c of 6.5 already defines diabetes.

    How can we reverse insulin resistance?

    Insulin resistance symptoms can be reversed by starting to decrease the levels of insulin in the blood. As insulin levels drop, then the body starts to respond better to insulin. The best and fastest way to drop insulin levels is by decreasing the ingestion of food that raises insulin levels. The foods that most raise insulin are carbohydrates such as sugars, but also less obvious sugars such as pasta, rice, bread, pizza, potatoes, sweet potatoes, fruits, corn, and legumes.

    Besides food, other things will help improve insulin resistance. This includes sleeping better, exercising, and decreasing emotional stress. So, if you are trying to figure out how to reverse insulin resistance naturally, those are some ways to go.

    Other things that may contribute to insulin resistance include certain medicines, such as glucocorticoids, some antipsychotics, and some medicines for HIV.

    Dr. Mariela Glandt is an endocrinologist specialized in Diabetes. She has recently opened the Glandt Center for Diabetes Care, a state of the art clinic in Tel Aviv.

     

     

     

     

    Insulin resistance and prediabetes occur when the body becomes insensitive to insulin.

    What is insulin?

    Insulin is a hormone made by the pancreas that helps glucose in your blood enter cells in your muscle, fat, and liver, where it’s used for energy. Glucose comes from the food you eat or it’s made by the liver when we are fasting. When glucose levels rise after you eat, your pancreas releases insulin into the blood, allowing the sugar to enter the cells and allowing the blood glucose levels to go back down to normal.

     

    What is insulin resistance?

    Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin and can’t easily take up glucose from your blood. Insulin resistance causes are highly correlated with abdominal fat (visceral fat). There are people that can handle a great deal of fat and don’t get sick, while there are others have less fat cells and therefore can contain limited amounts of fat. When the fat cells are overstuffed with fat, the fat starts sending a clear message that it does not have room for any more sugar.  This is called insulin resistance, and what it is essentially suggesting is that the body does not want any more sugar to come in. However, the pancreas must clear the high sugar from the blood and hence it makes more insulin to help glucose enter your cells. As long as your pancreas can make enough insulin to overcome your cells’ weak response to insulin, your blood glucose levels will stay in the healthy range. 

     

    Are there any problems with having insulin resistance, as long as glucose levels are in the normal range?

    Having normal sugar levels can be deceiving, giving a sense that there is no problem. However, high insulin levels, even with normal sugars, can be a problem. In the short run, high insulin levels make us hungry and make us gain weight. High insulin levels are also associated with hypertension and with dyslipidemia. In the long run, we know that high insulin levels are associated with higher rates of coronary artery disease, stroke, and cancer.

    What is prediabetes?

    When the pancreas is not able to keep up with the extra demand placed on it, then prediabetes sets in. This means your blood glucose levels are higher than normal but not high enough to be diagnosed as diabetes. One in every 3 adults has pre-diabetes. People with prediabetes have up to a 50 percent chance of developing diabetes over the next 5 to 10 years. Fortunately, type 2 diabetes can be prevented.

    What are the symptoms of insulin resistance and prediabetes?

    Insulin resistance and prediabetes usually have no symptoms. Unfortunately, doctors do not routinely check for insulin levels and diagnosed insulin resistance through other proxies. The presence of hypertension, high triglycerides, low HDL cholesterol, high uric acid, and fatty liver are all signs of insulin resistance. A HbA1c above 5.7 already points to insulin resistance. A HbA1c of 6.5 already defines diabetes.

    How can we reverse insulin resistance?

    Insulin resistance symptoms can be reversed by starting to decrease the levels of insulin in the blood. As insulin levels drop, then the body starts to respond better to insulin. The best and fastest way to drop insulin levels is by decreasing the ingestion of food that raises insulin levels. The foods that most raise insulin are carbohydrates such as sugars, but also less obvious sugars such as pasta, rice, bread, pizza, potatoes, sweet potatoes, fruits, corn, and legumes.

    Besides food, other things will help improve insulin resistance. This includes sleeping better, exercising, and decreasing emotional stress. So, if you are trying to figure out how to reverse insulin resistance naturally, those are some ways to go.

    Other things that may contribute to insulin resistance include certain medicines, such as glucocorticoids, some antipsychotics, and some medicines for HIV.

    Dr. Mariela Glandt is an endocrinologist specialized in Diabetes. She has recently opened the Glandt Center for Diabetes Care, a state of the art clinic in Tel Aviv.

     

     

     

     

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  • Diabetes and Prevention Diabetes and Prevention

    Posted on by Anabelle Savion

     diabetes prevention


    Diabetes is a heterogeneous chronic metabolic disorder that is characterized by elevated blood sugar levels, along with metabolic disturbances of all fuel providing compounds. All this happens either due to insulin resistance or deficit.  Disturbances of fat and protein metabolism in diabetes are as frequent as disturbances of glucose metabolism.

    Causes of diabetes are not fully understood. The family history of diabetes or genetics is a predisposing factor, but specific environmental factors like obesity, sedentary lifestyle and wrong kind of diet serve as triggering factors.

    Type 1 diabetes is a chronic autoimmune condition and is difficult to prevent. However preventing type 2 diabetes is possible with dietary and lifestyle changes.

    What happens in diabetes?

    Insulin is a hormone that is required by our body for energy generation and anabolic processes. In the deficit of insulin, our body cells are not able to properly use glucose for their energy needs; glucose fails to enter the muscles, liver and other cells of the body. In insulin deficit, all the construction processes in body slow down.

    Elevated glucose and disturbances of fat metabolism are harmful to the blood vessels. Thus diabetes is characterized by so-called macro and microvascular diseases. It is seen as damage to kidneys, eyesight, heart disease, increase in cases of stroke, neuropathies (damaged nerves), slower healing of wounds.

    Skin is one organ which becomes susceptible to infections. Due to a loss of sensation of limbs, chances of injury to extremities are elevated. Once injured, owing to neuropathies, inadequate blood supply, and persistent infections, healing process becomes painfully slow. In some individual’s chronic ulcers of limbs persist for months or even years. Infection of lower limbs is one of the leading non-traumatic causes of amputations.

    Preventing diabetes

    Diabetes is primarily a disease of lifestyle. Thus one of the most effective ways to stop this disorder is weight loss, dietary measures, and regular exercise.

    Weight loss: modern research shows that even 5-10% reduction in body weight (in obese people), may reduce the risk of developing diabetes by several times.

    Dietary measures: cutting back on refined carbs and sugary drinks will help maintain stable blood sugar levels and reduce the risk for diabetes. A registered dietitian (RD) or certified diabetes educator (CDE) can help create meal plans. The goal of the meal plan is to control blood glucose level and keep it in the healthy, normal range. 

    Regular exercise: a sedentary lifestyle has often been named are the number one killer of the 21st century. There is increasing evidence that sedentary lifestyle is causing more diseases than all other factors. Diabetes prevention studies carried out in the US, Europe, and Asian nations have shown that 150 minutes of aerobic exercise a week decreases the risk of developing diabetes by 50-70%. The minimum recommendation is of exercising at least 30 minutes five times a week.

     

    Skincare in diabetes

    Skin diseases in diabetes occur due to peripheral neuropathy causing loss of sensation, autonomic neuropathy leading to the dry and flaky skin, and inadequate blood supply due to diseased blood vessels. In diabetes, even a small scratch may get infected, because of elevated blood glucose level and slow down of the healing process, skin infections and ulcers are challenging to cure.

    Individuals living with diabetes have to take better care of their skin. It is recommended that people who have diabetes should check their feet on a daily basis, and should pay particular attention to the skincare, by regularly using hydrating agents along with anti-infective properties. Non-chemical based, natural creams and lotions may be especially beneficial in prevention and treatment of skin problems.

    Thus to prevent dry and cracked skin, it is highly recommended that a person uses moisturizer on a daily basis, not just any moisturizer, but one with anti-inflammatory and anti-microbial properties that can prevent the infection, help in healing the damage that has already occurred and can prevent or treat inflammation and swelling. Products based on natural ingredients are preferred as they are less irritating to skin on regular use.

     

     

     

     diabetes prevention


    Diabetes is a heterogeneous chronic metabolic disorder that is characterized by elevated blood sugar levels, along with metabolic disturbances of all fuel providing compounds. All this happens either due to insulin resistance or deficit.  Disturbances of fat and protein metabolism in diabetes are as frequent as disturbances of glucose metabolism.

    Causes of diabetes are not fully understood. The family history of diabetes or genetics is a predisposing factor, but specific environmental factors like obesity, sedentary lifestyle and wrong kind of diet serve as triggering factors.

    Type 1 diabetes is a chronic autoimmune condition and is difficult to prevent. However preventing type 2 diabetes is possible with dietary and lifestyle changes.

    What happens in diabetes?

    Insulin is a hormone that is required by our body for energy generation and anabolic processes. In the deficit of insulin, our body cells are not able to properly use glucose for their energy needs; glucose fails to enter the muscles, liver and other cells of the body. In insulin deficit, all the construction processes in body slow down.

    Elevated glucose and disturbances of fat metabolism are harmful to the blood vessels. Thus diabetes is characterized by so-called macro and microvascular diseases. It is seen as damage to kidneys, eyesight, heart disease, increase in cases of stroke, neuropathies (damaged nerves), slower healing of wounds.

    Skin is one organ which becomes susceptible to infections. Due to a loss of sensation of limbs, chances of injury to extremities are elevated. Once injured, owing to neuropathies, inadequate blood supply, and persistent infections, healing process becomes painfully slow. In some individual’s chronic ulcers of limbs persist for months or even years. Infection of lower limbs is one of the leading non-traumatic causes of amputations.

    Preventing diabetes

    Diabetes is primarily a disease of lifestyle. Thus one of the most effective ways to stop this disorder is weight loss, dietary measures, and regular exercise.

    Weight loss: modern research shows that even 5-10% reduction in body weight (in obese people), may reduce the risk of developing diabetes by several times.

    Dietary measures: cutting back on refined carbs and sugary drinks will help maintain stable blood sugar levels and reduce the risk for diabetes. A registered dietitian (RD) or certified diabetes educator (CDE) can help create meal plans. The goal of the meal plan is to control blood glucose level and keep it in the healthy, normal range. 

    Regular exercise: a sedentary lifestyle has often been named are the number one killer of the 21st century. There is increasing evidence that sedentary lifestyle is causing more diseases than all other factors. Diabetes prevention studies carried out in the US, Europe, and Asian nations have shown that 150 minutes of aerobic exercise a week decreases the risk of developing diabetes by 50-70%. The minimum recommendation is of exercising at least 30 minutes five times a week.

     

    Skincare in diabetes

    Skin diseases in diabetes occur due to peripheral neuropathy causing loss of sensation, autonomic neuropathy leading to the dry and flaky skin, and inadequate blood supply due to diseased blood vessels. In diabetes, even a small scratch may get infected, because of elevated blood glucose level and slow down of the healing process, skin infections and ulcers are challenging to cure.

    Individuals living with diabetes have to take better care of their skin. It is recommended that people who have diabetes should check their feet on a daily basis, and should pay particular attention to the skincare, by regularly using hydrating agents along with anti-infective properties. Non-chemical based, natural creams and lotions may be especially beneficial in prevention and treatment of skin problems.

    Thus to prevent dry and cracked skin, it is highly recommended that a person uses moisturizer on a daily basis, not just any moisturizer, but one with anti-inflammatory and anti-microbial properties that can prevent the infection, help in healing the damage that has already occurred and can prevent or treat inflammation and swelling. Products based on natural ingredients are preferred as they are less irritating to skin on regular use.

     

     

     

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  • Tips for Preventing Diabetic Foot Ulcers and Wounds Tips for Preventing Diabetic Foot Ulcers and Wounds

    Posted on by Anabelle Savion

                                                  

     

    According to the World Health Organization, 8.5% of the world’s adult population is diabetic and the prevalence is rising. Diabetes mellitus is a chronic disorder of carbohydrate metabolism, that is characterized by elevated blood sugar (hyperglycemia) due to lack of insulin or inability of the body to respond to the available insulin. The persistent elevated blood sugar has deleterious effects (complications) on various body tissue/organs.

    Diabetic foot ulcer is one of the common and serious complications in diabetic patients. The ulceration of the foot, if not treated promptly, may lead to gangrene of the whole foot necessitating amputation. Diabetes Mellitus is the leading cause of non-traumatic foot/leg amputation.

    Narrowing of the blood vessels with reduction in blood supply to the lower extremities, inability to feel pain and pressure sensations due to damage to the peripheral nerves and infections are some of the predisposing factors for diabetic wound.

    Ulcer on the leg and foot significantly affects the quality of life in diabetic patients. Thus, nothing can be more important than prevention. Diabetic wound is largely preventable and some of the prevention tips are as follows:

    Ensure optimal blood sugar control: since most of the complications of diabetes are directly or indirectly due to elevated blood sugar, adequate blood sugar control will help reduce the risk of diabetic ulcer.

    Avoid too loose/tight footwear: when it is too tight, it will exert pressure on the bony prominences and this may lead to ulceration. When it is too loose, your foot can slip out of it and you may step on stones/sharp object. Your footwear should provide adequate cushioning.

    Get your feet inspected daily: You can do this by yourself and allow your family members to assist you. This will ensure that any skin changes such as blisters or cracks can be detected early before a wound develops. Regular foot examination by your physician is also important.

    Ensure extra care while cutting your toe nails, if possible, don’t do it yourself. Diabetes also affects the eye and a poor sight can make you injure yourself while cutting your toe nails.

    Do not smoke or quit smoking: smoking will further compromise blood supply to your feet and prevents healing if a wound should develop.

    Use moisturizers: one of the signs that your foot is at risk of ulceration is dry skin. This is a pointer to inadequate blood supply and dry skin easily get wounded. Moisturize your skin to prevent chapping, especially in cold or windy weather. Don’t put lotions between toes. The extra moisture in this area can cause fungus to grow.

    Treat cuts right away. Wash minor cuts with soap and water and apply antiseptic ointment.

    Avoid harsh ingredients or chemicals and instead choose a mild shampoo and soap.

    LAVIOR has therefore developed natural products, whose efficacies have been clinically proven, regarding prevention and treatment of diabetic ulcers. These products include: M-CARE & D-CARE, and a mild shampoo H-CARE.

    M-CARE is an organic moisturizer that will prevent dry skin and significantly reduce the risk of ulceration or cracks. It is steroid-free and does not provoke allergic reaction. It also has antibacterial and anti-inflammatory properties, making it a good preventive agent.

    D-CARE is another product that can serve both preventive and therapeutic functions. It does not contain steroids, it does not provoke allergy, and it soothes the skin, preventing cracks and fissures. It also accelerates wound healing by its anti-inflammatory and antibacterial properties.

    H-CARE is a plant based chemical free and non-irritant formula safe for all skin types including diabetics and those with sensitive skin.

     

     

                                                  

     

    According to the World Health Organization, 8.5% of the world’s adult population is diabetic and the prevalence is rising. Diabetes mellitus is a chronic disorder of carbohydrate metabolism, that is characterized by elevated blood sugar (hyperglycemia) due to lack of insulin or inability of the body to respond to the available insulin. The persistent elevated blood sugar has deleterious effects (complications) on various body tissue/organs.

    Diabetic foot ulcer is one of the common and serious complications in diabetic patients. The ulceration of the foot, if not treated promptly, may lead to gangrene of the whole foot necessitating amputation. Diabetes Mellitus is the leading cause of non-traumatic foot/leg amputation.

    Narrowing of the blood vessels with reduction in blood supply to the lower extremities, inability to feel pain and pressure sensations due to damage to the peripheral nerves and infections are some of the predisposing factors for diabetic wound.

    Ulcer on the leg and foot significantly affects the quality of life in diabetic patients. Thus, nothing can be more important than prevention. Diabetic wound is largely preventable and some of the prevention tips are as follows:

    Ensure optimal blood sugar control: since most of the complications of diabetes are directly or indirectly due to elevated blood sugar, adequate blood sugar control will help reduce the risk of diabetic ulcer.

    Avoid too loose/tight footwear: when it is too tight, it will exert pressure on the bony prominences and this may lead to ulceration. When it is too loose, your foot can slip out of it and you may step on stones/sharp object. Your footwear should provide adequate cushioning.

    Get your feet inspected daily: You can do this by yourself and allow your family members to assist you. This will ensure that any skin changes such as blisters or cracks can be detected early before a wound develops. Regular foot examination by your physician is also important.

    Ensure extra care while cutting your toe nails, if possible, don’t do it yourself. Diabetes also affects the eye and a poor sight can make you injure yourself while cutting your toe nails.

    Do not smoke or quit smoking: smoking will further compromise blood supply to your feet and prevents healing if a wound should develop.

    Use moisturizers: one of the signs that your foot is at risk of ulceration is dry skin. This is a pointer to inadequate blood supply and dry skin easily get wounded. Moisturize your skin to prevent chapping, especially in cold or windy weather. Don’t put lotions between toes. The extra moisture in this area can cause fungus to grow.

    Treat cuts right away. Wash minor cuts with soap and water and apply antiseptic ointment.

    Avoid harsh ingredients or chemicals and instead choose a mild shampoo and soap.

    LAVIOR has therefore developed natural products, whose efficacies have been clinically proven, regarding prevention and treatment of diabetic ulcers. These products include: M-CARE & D-CARE, and a mild shampoo H-CARE.

    M-CARE is an organic moisturizer that will prevent dry skin and significantly reduce the risk of ulceration or cracks. It is steroid-free and does not provoke allergic reaction. It also has antibacterial and anti-inflammatory properties, making it a good preventive agent.

    D-CARE is another product that can serve both preventive and therapeutic functions. It does not contain steroids, it does not provoke allergy, and it soothes the skin, preventing cracks and fissures. It also accelerates wound healing by its anti-inflammatory and antibacterial properties.

    H-CARE is a plant based chemical free and non-irritant formula safe for all skin types including diabetics and those with sensitive skin.

     

     

    Read more